Semen Harbors Wide Range of Viruses

From Drugs.com - September 13, 2017

Semen Harbors Wide Range of Viruses

WEDNESDAY, Sept. 13, 2017 -- Human semen provides a potential hiding place and breeding ground for a host of dangerous viruses, a new evidence review reports.

The analysis of current medical literature revealed genetic evidence of 27 infectious viruses found in semen, including dread-inducing agents like Zika, Ebola, Marburg, Lassa fever and chikungunya, along with mumps, Epstein-Barr and chicken pox.

"Clinicians and researchers need to consider the possibility that traditionally non-sexually transmitted viruses can persist in semen, and this therefore raises the possibility of sexual transmission," said lead researcher Alex Salam. He is a clinical researcher with the University of Oxford's epidemic diseases research group in the United Kingdom.

However, the presence of viruses in semen does not mean that every virus can be sexually transmitted, the researchers noted.

"Detection means that evidence of viral genetic material or viral protein was found in semen," Salam said. "It's important to note that this does not mean that the virus is viable, i.e., capable of replicating. To prove this, the virus needs to be isolated and grown in cells or animals. For many of the viruses, this test has not been done, so we do not know whether virus is viable or not."

Sex also might not be the most efficient means of transmission for these viruses. Infectious disease expert Dr. Pritish Tosh noted that scores more cases of Zika have been passed along via mosquito bites than have been transmitted through sexual contact.

People also are much more likely to catch Epstein-Barr virus, which causes mononucleosis, from another person's unprotected sneeze or cough than through sex, said Tosh, an associate professor with the Mayo Clinic in Rochester, Minn.

"In some ways it does not matter if it can be spread by semen if it also can be spread by saliva," Tosh added.

For this report, Salam and his colleagues reviewed more than 3,800 scientific articles published on viruses and semen. Their review resulted in a list of the 27 infectious viruses that have been found in human semen.

The list includes obvious culprits such as hepatitis viruses, herpes viruses and HIV. But it also includes a range of other viruses normally known to pass person-to-person via blood, saliva or other means.

For most of the viruses on the list, data regarding the possibility of sexual transmission is lacking, the researchers reported.

"It is unclear to what extent the viruses detected in semen can also be sexually transmitted," Salam said. "The virus needs to be viable, but this alone may not be enough for sexual transmission. For some, we found evidence of sexual transmission, but others we found no evidence one way or the other."

Tosh said that it makes sense that viruses would be able to set up shop in semen. "It's relatively easy for viruses to get in there, but relatively harder for the immune system to clear these viruses," he explained.


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