Medical Marijuana Won't Help Most Sick Kids

From - October 23, 2017

Medical Marijuana Wo not Help Most Sick Kids

MONDAY, Oct. 23, 2017 -- Medical marijuana appears to hold only limited promise for sick children and teenagers, a new review suggests.

It can help kids fighting cancer with chemotherapy-related nausea and vomiting, and it can control seizures somewhat in children with epilepsy, said study author Dr. Shane Shucheng Wong. He is a psychiatrist with Massachusetts General Hospital, in Boston.

But there's not enough evidence to say that medical marijuana can help kids with any other medical conditions, such as neuropathic pain, post-traumatic stress disorder (PTSD) or Tourette's syndrome, Wong added.

Medical marijuana is now legal in 29 states and the District of Columbia, making it potentially available as a medication for kids.

"Children and adolescents can legally access medical cannabis if they have certification from a doctor and from their legal guardian," Wong said. "As a result, doctors and families really need to understand what we know and what we do not yet know about medical cannabis to make the best decision for the child's health."

A review of medical literature revealed 21 studies directly examining the potential benefits of medical pot for children and teens, the researchers said. These included six studies on the impact pot has on chemotherapy-induced nausea and vomiting, and 11 studies on epilepsy.

Studies involving pot's usefulness in controlling chemotherapy side effects -- four of which were randomized, controlled trials -- found that medical cannabis was significantly better than anti-nausea drugs, according to the review.

The active intoxicating ingredient in pot, THC, appears to reduce nausea and vomiting in these young patients, the trials showed.

Since 1985, there have been two drugs approved by the U.S. Food and Drug Administration to treat chemo side effects that are forms of synthetic THC, Wong said. The drugs are dronabinol (Marinol) and nabilone (Cesamet).

The epilepsy studies, which included one randomized trial, showed that another chemical compound in pot called cannabidiol (CBD) appears to reduce the frequency of seizures in children and teens. CBD does not cause intoxication.

An epilepsy drug based on CBD, Epidiolex, is currently in fast-track phase 3 trials "to try to show enough scientific evidence to support its use for potential [FDA] approval," Wong said. "It certainly is promising."

Research is lacking on any other uses for medical marijuana in children and teenagers, the researchers concluded.

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